The city as a laboratory
Keywords:
Circadian rhythms, zoonotic surveillance, viral metagenomics, One HealthAbstract
Cities are ecosystems where rats, pigeons, and bats can function as “living sensors” of biological change. By living among waste, water, food sources, pets, and sewers, they accumulate traces that can reveal early warning signs of risk. This article proposes getting ahead of potential problems through simple, non-invasive sampling, before cases of infection or outbreaks appear in people and animals, or signs of environmental deterioration emerge. These signals include microbes, viruses, and fragments of genetic material. Integrated across several layers, they can be summarized in a zone-based traffic-light system that measures the level of attention required in each area.
References
Meurens, F., Dunoyer, C., Fourichon, C., Gerdts, V., Haddad, N., Kortekaas, J., et al. (2021). Animal board invited review: Risks of zoonotic disease emergence at the interface of wildlife and livestock systems. Animal, 15(6), 100241. https://doi.org/10.1016/j.animal.2021.100241
Schilling, A. K., Mazzamuto, M. V., & Romeo, C. (2022). A review of non-invasive sampling in wildlife disease and health research: What’s new? Animals, 12(13), 1719. https://doi.org/10.3390/ani12131719
Kimura, M., Kothari, S., Gohir, W., Camargo, J. F., & Husain, S. (2023). MicroRNAs in infectious diseases: Potential diagnostic biomarkers and therapeutic targets. Clinical Microbiology Reviews, 36(4), e00015-23. https://doi.org/10.1128/cmr.00015-23
Yan, H., Jiao, H., Liu, Q., Zhang, Z., Xiong, Q., Wang, B. J., et al. (2021). ACE2 receptor usage reveals variation in susceptibility to SARS-CoV and SARS-CoV-2 infection among bat species. Nature Ecology & Evolution, 5(5), 600–608. https://doi.org/10.1038/s41559-021-01407-1
Ribas, M. P., García-Ulloa, M., Espunyes, J., & Cabezón, O. (2023). Improving the assessment of ecosystem and wildlife health: Microbiome as an early indicator. Current Opinion in Biotechnology, 81, 102923. https://doi.org/10.1016/j.copbio.2023.102923
Nguyen, N. H., Song, Z., Bates, S. T., Branco, S., Tedersoo, L., Menke, J., et al. (2016). FUNGuild: An open annotation tool for parsing fungal community datasets by ecological guild. Fungal Ecology, 20, 241–248. https://doi.org/10.1016/j.funeco.2015.06.006
Elbehiry, A., & Abalkhail, A. (2025). Metagenomic next-generation sequencing in infectious diseases: Clinical applications, translational challenges, and future directions. Diagnostics, 15(16), 1991. https://doi.org/10.3390/diagnostics15161991
Mejias, A., Cohen, S., Glowinski, R., & Ramilo, O. (2021). Host transcriptional signatures as predictive markers of infection in children. Current Opinion in Infectious Diseases, 34(5), 552–558. https://doi.org/10.1097/QCO.0000000000000750
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Revista de divulgación científica iBIO

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Self-archiving or deposit of the works in their post-publication version (editorial version) is permitted in any personal, institutional or thematic repository, social or scientific networks. The above applies from the moment of publication of the article in question on the website of the Revista de divulgación científica iBIO.