VIRI and the journey of targeted medicine

Authors

  • Francisca Villanueva-Flores Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada, Instituto Politécnico Nacional. Boulevard de la Tecnología, 1036 Z-1, P 2/2, 62790 Atlacholoaya, Morelos, México. https://orcid.org/0000-0001-6092-4211
  • Igor García-Atutxa Escuela Politécnica Superior. Universidad Católica de Murcia (UCAM) Av. de los Jerónimos, 135, 30107, Murcia, España. https://orcid.org/0009-0002-1551-2685

Keywords:

Virus-like particles, VLPs, nanocarriers, targeted delivery, anticancer therapy

Abstract

This science communication story presents Athena, a science student who designs VIRI, a virus-like particle (VLP) that transports drugs to tumor cells. The story explains that VLPs resemble viruses on the outside because they retain a protein capsid, but they are empty on the inside and lack the genetic material required for replication, so they cannot cause disease. Instead, they function as vehicles that protect the medicine, recognize the correct cell, and release it at its destination. Thus, they show that a therapy requires protection, direction, and precision.

References

Mejía-Méndez, J. L., Vázquez-Duhalt, R., Hernández, L. R., Sánchez-Arreola, E., & Bach, H. (2022). Virus-like particles: Fundamentals and biomedical applications. International Journal of Molecular Sciences, 23(15), 8579. doi: 10.3390/ijms23158579

He, J., Yu, L., Lin, X., Liu, X., Zhang, Y., Yang, F., & Deng, W. (2022). Virus-like particles as nanocarriers for intracellular delivery of biomolecules and compounds. Viruses, 14(9), 1905. doi: 10.3390/v14091905

Ikwuagwu, B., & Tullman-Ercek, D. (2022). Virus-like particles for drug delivery: A review of methods and applications. Current Opinion in Biotechnology, 78, 102785. doi: 10.1016/j.copbio.2022.102785

Travassos, R., Martins, S. A., Fernandes, A., Correia, J. D. G., & Melo, R. (2024). Tailored viral-like particles as drivers of medical breakthroughs. International Journal of Molecular Sciences, 25(12), 6699. doi: 10.3390/ijms25126699

Kim, K. R., Lee, A. S., Kim, S. M., Heo, H. R., & Kim, C. S. (2023). Virus-like nanoparticles as a theranostic platform for cancer. Frontiers in Bioengineering and Biotechnology, 10, 1106767. doi: 10.3389/fbioe.2022.1106767

Published

2026-07-04

How to Cite

Villanueva-Flores, F., & García-Atutxa, I. (2026). VIRI and the journey of targeted medicine . Revista De divulgación científica IBIO, 8(3), 390. Retrieved from https://revistaibio.com/ojs33/index.php/main/article/view/390

Issue

Section

Art in science and engineering

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