ATAC-seq, the key to unlock the genome secrets
Keywords:
Chromatin, Transposase, Massive-sequencing, DNA-compaction, BioinformaticsAbstract
The genome of each cell is huge and highly compacted within the nucleus as chromatin. However, not all DNA-encoded information is required simultaneously; only a subset of genes is activated depending on the cell type and specific conditions. Chromatin contains inaccessible regions due to its high compaction level, while accessible areas correspond to functionally active genes. ATAC-seq is a powerful technique for accurately identifying accessible regions of the genome, offering critical insights into gene regulation and chromatin organization.
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