The oral microbiome: The invisible ecosystem that impacts your health

Authors

  • Ana Sofía Alvarado Bautista PhyloGenomicsUD - Semillero de Investigación en Filogenética, Evolución y Ciencias Ómicas. Grupo de Investigación MATTOPO. Facultad de Ciencias Matemáticas y Naturales. Universidad Distrital Francisco José de Caldas, Bogotá, Colombia. Micrap - Semillero de Investigación en Microbiología aplicada. Grupo de Investigación en Biodiversidad de Alta Montaña. Facultad de Ciencias Matemáticas y Naturales. Universidad Distrital Francisco José de Caldas, Bogotá, Colombia.
  • Julian Andres Largo Lopez PhyloGenomicsUD - Semillero de Investigación en Filogenética, Evolución y Ciencias Ómicas. Grupo de Investigación MATTOPO. Facultad de Ciencias Matemáticas y Naturales. Universidad Distrital Francisco José de Caldas, Bogotá, Colombia. Micrap - Semillero de Investigación en Microbiología aplicada. Grupo de Investigación en Biodiversidad de Alta Montaña. Facultad de Ciencias Matemáticas y Naturales. Universidad Distrital Francisco José de Caldas, Bogotá, Colombia.

Keywords:

Disease, Microbiome, Oral cavity

Abstract

The microorganisms of the human microbiome are a community that is more diverse, variable, and important than we know. Within the oral cavity, they serve as protective entities against external pathogens but can also contribute to the development of oral diseases and trigger systemic illnesses. It is well known that sugar-rich diets favor acidogenic species such as S. mutans, involved in the onset of caries. Even lifestyle habits can influence the development of diseases such as oral cancer. This highlights the importance of maintaining good oral hygiene habits (such as tooth brushing), as well as a balanced and low-sugar diet.

References

Althani, A. A., Marei, H. E., Hamdi, W. S., Nasrallah, G. K., El Zowalaty, M. E., Al Khodor, S., Al-Asmakh, M., Abdel-Aziz, H., Cenciarelli, C. (2016). Human Microbiome and its Association With Health and Diseases. Journal of Cellular Physiology, 231(8), 1688–1694. https://doi.org/10.1002/jcp.25284

Dewhirst, F. E., Chen, T., Izard, J., Paster, B. J., Tanner, A. C., Yu, W. H., Lakshmanan, A., Wade, W. G. (2010). The human oral microbiome. Journal of bacteriology, 192(19), 5002-5017. https://doi.org/10.1128/jb.00542-10

Verma, D., Garg, P.K. & Dubey, A.K. (2018). Insights into the human oral microbiome. Arch Microbiol 200, 525–540. https://doi.org/10.1007/s00203-018-1505-3

Adler, C. J., Dobney, K., Weyrich, L. S., Kaidonis, J., Walker, A. W., Haak, W., Bradshaw, C. J. A., Townsend, G., Sołtysiak, A., Alt, K. W., Parkhill, J., Cooper, A. (2013). Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions. Nature genetics, 45(4), 450-455. https://doi.org/10.1038/ng.2536

Rajasekaran, J. J., Krishnamurthy, H. K., Bosco, J., Jayaraman, V., Krishna, K., Wang, T., Bei, K. (2024). Oral Microbiome: A Review of Its Impact on Oral and Systemic Health. Microorganisms, 12(9), 1797. https://doi.org/10.3390/microorganisms12091797

Pizarro, M. C., & Lillo, O. C. (2014). La caries dental: una enfermedad que se puede prevenir. Anales de Pediatría Continuada, 12(3), 147-151. https://doi.org/10.1016/s1696-2818(14)70184-2

Silva, M. L., Diz-Iglesias, P., Seoane-Romero, J., Quintas, V., Méndez-Brea, F., & Varela-Centelles, P. (2016). Actualización en medicina de familia: patología periodontal. Medicina de Familia SEMERGEN, 43(2), 141-148. https://doi.org/10.1016/j.semerg.2016.02.005

Laumen, J., Van Dijck, C., Manoharan-Basil, S., De Block, T., Abdellati, S., Xavier, B., Malhotra-Kumar, S., & Kenyon, C. (2024). The effect of daily usage of Listerine Cool Mint mouthwash on the oropharyngeal microbiome: a substudy of the PReGo trial. Journal Of Medical Microbiology, 73(6). https://doi.org/10.1099/jmm.0.001830

Published

2025-10-08

How to Cite

Alvarado Bautista, A. S., & Largo Lopez, J. A. (2025). The oral microbiome: The invisible ecosystem that impacts your health. Revista De divulgación científica IBIO, 8(1), 249. Retrieved from http://revistaibio.com/ojs33/index.php/main/article/view/249