DNA methylation in cancer and its diagnosis
Keywords:
Epigenetics, DNA methylation, CancerAbstract
DNA methylation is an epigenetic mechanism that modifies gene expression without changing the DNA sequence. It is a reversible process resulting from the interaction of various factors, such as age, diet, environment, and genetic makeup. Under normal conditions, it participates in the regulation of genomic imprinting and the maintenance of DNA integrity. However, tumor development involves changes in the level and pattern of methylation in specific regions, which can be used for early cancer diagnosis.
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