Viruses at the service of science: gene silencing and expression in plants
Keywords:
Virus, VOX, VIGSAbstract
For centuries, we observed plants from the outside only, based on their physical properties, and fruit yield. Today, biotechnology opens an inner window with the help of an unexpected ally: domesticated plant viruses, so-called “viral vectors”. Due to their ability to reproduce massively these vectors allow scientists to produce huge amounts of protein, or the temporal silencing of specific genes. With this, scientist can learn what genes do, or make a lot of protein for vaccines and medicine. Recent discoveries have also allowed these viral vectors to do precision gene editing.
References
Wang, Z., Cao, S., Xu, X., He, Y., Shou, W., Munaiz, E. D., Yu, C., & Shen, J. (2023). Application and expansion of virus-Induced Gene Silencing for functional studies in vegetables. Horticulturae, 9(8), 934. https://doi.org/10.3390/horticulturae9080934
Rössner, C., Lotz, D., & Becker, A. (2022). VIGS goes viral: How VIGS transforms our understanding of plant science. Annual Review of Plant Biology, 73(1), 703–728. https://doi.org/10.1146/annurev-arplant-102820020542
Segre, J. (2025). Virus. In Talking Glossary of Genomic and Genetic Terms, Genome.gov. https://www.genome.gov/genetics-glossary/Virus Consultado: 09 de septiembre, 2025.
Jiang, M.-C., Hu, C.-C., Lin, N.-S., & Hsu, Y.-H. (2019). Production of human IFNγ protein in Nicotiana benthamiana plant through an enhanced expression system based on Bamboo mosaic virus. Viruses, 11(6), 509. https://doi.org/10.3390/v11060509
Tang, Q., Wei, S., Chen, Z., Zheng, X., Tu, P., & Tao, F. (2024). The reverse genetic as a potential of virus‐induced gene silencing in tomato biology. Food Frontiers, 5(6), 2498–2514. https://doi.org/10.1002/fft2.455
Killiny, N., Nehela, Y., Hajeri, S., Gowda, S., & Stelinski, L. L. (2025). Virus-induced gene silencing simultaneously exploits “attract and kill” traits in plants and insects to manage huanglongbing. Horticulture Research, 12(2), uhae311. https://doi.org/10.1093/hr/uhae311
Awan, M. J. A., Akram, A., Amin, I., & Mansoor, S. (2023). Viral vectors as carriers of genome-editing reagents. Trends in Plant Science, 28(9), 981–983. https://doi.org/10.1016/j.tplants.2023.05.010
AgbioInvestor. (2025). GM Approvals Database. Agbioinvestor.com. https://gm.agbioinvestor.com/approvals-database Consultado: 09 de septiembre, 2025.
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