Viruses at the service of science: gene silencing and expression in plants

Authors

  • Mariana Sepúlveda Pérez Unidad de Biotecnología Vegetal, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, A.C. (CIATEJ), SECIHTI, Zapopan, Jalisco, 45019, México.
  • Julio Armando Massange Sánchez Unidad de Biotecnología Vegetal, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, A.C. (CIATEJ), SECIHTI, Zapopan, Jalisco, 45019, México.
  • Rafael Urrea López Unidad de Biotecnología Vegetal, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, A.C. (CIATEJ), SECIHTI, Zapopan, Jalisco, 45019, México. https://orcid.org/0000-0002-0368-6007

Keywords:

Virus, VOX, VIGS

Abstract

For centuries, we observed plants from the outside only, based on their physical properties, and fruit yield. Today, biotechnology opens an inner window with the help of an unexpected ally: domesticated plant viruses, so-called “viral vectors”. Due to their ability to reproduce massively these vectors allow scientists to produce huge amounts of protein, or the temporal silencing of specific genes. With this, scientist can learn what genes do, or make a lot of protein for vaccines and medicine. Recent discoveries have also allowed these viral vectors to do precision gene editing.

References

Wang, Z., Cao, S., Xu, X., He, Y., Shou, W., Munaiz, E. D., Yu, C., & Shen, J. (2023). Application and expansion of virus-Induced Gene Silencing for functional studies in vegetables. Horticulturae, 9(8), 934. https://doi.org/10.3390/horticulturae9080934

Rössner, C., Lotz, D., & Becker, A. (2022). VIGS goes viral: How VIGS transforms our understanding of plant science. Annual Review of Plant Biology, 73(1), 703–728. https://doi.org/10.1146/annurev-arplant-102820020542

Segre, J. (2025). Virus. In Talking Glossary of Genomic and Genetic Terms, Genome.gov. https://www.genome.gov/genetics-glossary/Virus Consultado: 09 de septiembre, 2025.

Jiang, M.-C., Hu, C.-C., Lin, N.-S., & Hsu, Y.-H. (2019). Production of human IFNγ protein in Nicotiana benthamiana plant through an enhanced expression system based on Bamboo mosaic virus. Viruses, 11(6), 509. https://doi.org/10.3390/v11060509

Tang, Q., Wei, S., Chen, Z., Zheng, X., Tu, P., & Tao, F. (2024). The reverse genetic as a potential of virus‐induced gene silencing in tomato biology. Food Frontiers, 5(6), 2498–2514. https://doi.org/10.1002/fft2.455

Killiny, N., Nehela, Y., Hajeri, S., Gowda, S., & Stelinski, L. L. (2025). Virus-induced gene silencing simultaneously exploits “attract and kill” traits in plants and insects to manage huanglongbing. Horticulture Research, 12(2), uhae311. https://doi.org/10.1093/hr/uhae311

Awan, M. J. A., Akram, A., Amin, I., & Mansoor, S. (2023). Viral vectors as carriers of genome-editing reagents. Trends in Plant Science, 28(9), 981–983. https://doi.org/10.1016/j.tplants.2023.05.010

AgbioInvestor. (2025). GM Approvals Database. Agbioinvestor.com. https://gm.agbioinvestor.com/approvals-database Consultado: 09 de septiembre, 2025.

Published

2025-10-14

How to Cite

Sepúlveda Pérez, M., Massange Sánchez, J. A., & Urrea López, R. (2025). Viruses at the service of science: gene silencing and expression in plants. Revista De divulgación científica IBIO, 8(1), 259. Retrieved from http://revistaibio.com/ojs33/index.php/main/article/view/259

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