The world through a sheet of light: Lightsheet microscopy

Authors

  • Gonzalo González-Domínguez Posgrado de ciencias bioquímicas de la UNAM.
  • Javier Rodrigo Prado-Baeza Posgrado de ciencias biológicas de la UNAM.

Keywords:

Microscopy, lightsheet, biomedicine

Abstract

Human curiosity has always driven us to learn more about the world around us, particularly about what lies beyond our vision. Observing the microscopic world has always been of great interest to us. This led to the creation of a remarkable tool known as the microscope, which over time has evolved, acquiring countless applications. Among the most advanced microscopes today is the light-sheet microscope, an invaluable tool in the field of biomedicine, which will be discussed in greater detail in this work.

References

Diosdi A. et al. Single-cell light-sheet fluorescence 3D images of tumour-stroma spheroid multicultures. Sci Data. 2025 Mar 24;12(1):492.

Di Giovanna A. et al. Whole-Brain Vasculature Reconstruction at the Single Capillary Level. Sci Rep. 2018 Aug 22;8(1):12573.

Mai H. et al. Whole-body cellular mapping in mouse using standard IgG antibodies. Nat Biotechnol. 2024 Apr;42(4):617-627.

Published

2026-07-24

How to Cite

González-Domínguez , G., & Prado-Baeza, J. R. (2026). The world through a sheet of light: Lightsheet microscopy . Revista De divulgación científica IBIO, 8(3), 373. Retrieved from http://revistaibio.com/ojs33/index.php/main/article/view/373

Issue

Section

How does it work?