Smart polymers: Chains that know when to make the clean cut

Authors

  • Esperanza Peralta-Cuevas Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada, Instituto Politécnico Nacional, Boulevard de la Tecnología, 1036 Z-1, P 2/2, 62790 Atlacholoaya, Morelos, México.
  • Nahomi Y. Degollado-Hernández Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada, Instituto Politécnico Nacional, Boulevard de la Tecnología, 1036 Z-1, P 2/2, 62790 Atlacholoaya, Morelos, México. Universidad Tecnológica Emiliano Zapata del Estado de Morelos, Av. Universidad Tecnológica 1, Palo Escrito, 62765, Emiliano Zapata, Morelos, México.
  • Francisca Villanueva-Flores Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada, Instituto Politécnico Nacional, Boulevard de la Tecnología, 1036 Z-1, P 2/2, 62790 Atlacholoaya, Morelos, México.

Keywords:

Smart polymers, controlled drug release, stimulus-responsive

Abstract

Smart polymers are materials that respond to stimuli, such as temperature or pH, and alter their structure to release drugs in a controlled manner. They function as “molecular guardians” that act only at the precise moment and location, enhancing effectiveness and reducing side effects. At the National Polytechnic Institute (IPN), these principles have been applied to develop an intelligent dressing for chronic wounds, which releases antimicrobial and healing compounds upon detecting an infection. Its low cost facilitates large-scale production and access in vulnerable communities. This approach holds promise for future applications in oncology, regenerative medicine, and infection control.

References

Villanueva-Flores, F., Miranda-Hernández, M., Flores-Flores, J. O., Porras-Sanjuanico, A., Hu, H., Pérez-Martínez, L., Ramírez, O. T., & Palomares, L. A. (2019). Poly(vinyl alcohol co-vinyl acetate) as a novel scaffold for mammalian cell culture and controlled drug release. Journal of Materials Science, 54(10), 7867–7882. https://doi.org/10.1007/s10853-019-03402-1

Villanueva-Flores, F., & Palomares, L. A. (2022). Low-cost poly(vinyl formal) for heavy metal removal from water of a polluted river. Journal of Water Reuse and Desalination, 12(1), 52–65. https://doi.org/10.2166/wrd.2022.077

Heskins, M., & Guillet, J. E. (1968). Solution Properties of Poly(N-isopropylacrylamide). Journal of Macromolecular Science: Part A - Chemistry, 2(8), 1441–1455. https://doi.org/10.1080/10601326808051910

Convatec. (2024). AquacelTM. https://www.convatec.com/es-co/productos/cuidado-avanzado-de-heridas/marcas-comerciales/pc-wound-aquacel/

Villalobos, C. (31 de mayo de 2024). Parche inteligente para tratar heridas crónicas. Gaceta Politécnica, Instituto Politécnico Nacional (IPN), 174, 13–15.

Balcerak-Woźniak, A., Dzwonkowska-Zarzycka, M., & Kabatc-Borcz, J. (2024). A Comprehensive Review of Stimuli-Responsive Smart Polymer Materials—Recent Advances and Future Perspectives. Materials, 17(17), 4255. https://doi.org/10.3390/ma17174255

Published

2025-11-19

How to Cite

Peralta-Cuevas, E., Degollado-Hernández, N. Y., & Villanueva-Flores, F. (2025). Smart polymers: Chains that know when to make the clean cut. Revista De divulgación científica IBIO, 8(1), 291. Retrieved from http://revistaibio.com/ojs33/index.php/main/article/view/291

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